Clinical Trial Services
We, at CVS Health Clinical Trial Services™, are working to advance health care by making clinical trial research more accessible to all communities, with a focus on improving health outcomes and enhancing the effectiveness of clinical trials.
The need for change
Clinical trials are important research programs designed to evaluate the safety and effectiveness of new medicines, vaccines, devices and other therapies. They are required by the U.S. Food and Drug Administration to evaluate whether such therapeutics should be approved for use in clinical practice and by patients. Lasting months or even years, these studies are critical to the advancement of health care and depend on the participation of clinically-appropriate volunteers.
Despite their importance, 80% of clinical trials do not meet designated patient enrollment deadlines, with over 10% of research sites failing to enroll even one patient. Of patients actually enrolled in trials, an average of 30% drop out for reasons including inconvenient trial site location, complex participation requirements and trial duration.
Clinical Trial Services in action
During a nine-month contract with the Federal Government, CVS Health Clinical Trial Services (CTS) analyzed COVID-19 test results from retail locations in 35 states and Washington, D.C. The data analyzed provided trends and patterns of COVID-19 infections, illustrating the importance of real-time tracking. While the study was ongoing, CTS data delivered early identification of increases in COVID-19 infections and relative comparisons in infection rate between unvaccinated and fully vaccinated populations.
A recent COVID-19 trial required a large volume of COVID-19 positive patients to enroll in the trial within five days of their swab test. Through our engagement with communities across the U.S., we were able to engage approximately 4,000 interested and qualified individuals per week and invite them to participate in the study.
A primary objective of our efforts was to ensure representation of diverse populations in the study. Inclusion of individuals from varied races, age, ethnicities and gender provides a more complete view of the patient populations that can respond differently to therapies. We are proud to share that close to 49% of the individuals in this COVID-19 effort who opted in to learn more were from diverse populations.
We are reimagining clinical trials
From precision patient recruitment with a trial ready, diverse population to trial delivery and real-world evidence generation, we are working to make clinical research more effective and easier for people to access and to participate.
We have shown that clinical trial innovation is possible by keeping the people and communities we serve at the very heart of all that we do.
CVS Health is committed to advancing health care through a “human-centric” approach, leveraging our unmatched community connections, deep understanding of those we serve, and a trial experience built around the individual in ways that work best for them — in our clinics, in their homes, or virtually.
Our community connections and experience
We take great pride in the connections we have within our diverse communities around the country. This relationship is supported by our national presence and the local services that we offer to the people that come through our doors every day.
In fact, more than 85% of Americans live within 10 miles of a CVS retail health location where we offer over 125 health care services and administration of over 25 vaccines.
In addition to our established health care services, our experience also includes clinical trial support. We have delivered over 200 in-home clinical trials by Coram®, engaged and pre-screened hundreds of thousands of individuals for study participation, worked with top pharmaceutical and medical device companies on real-world evidence generation, and have contributed to a number of peer-reviewed research publications. Our model is reflective of the value achieved by keeping the patient at the core of what we do.
On the front lines, advancing healthcare
We have collaborated with the pharmaceutical industry to help facilitate clinical trials for investigational COVID-19 vaccines and treatments. Using a specially designed digital model and screening protocols, CVS Health engaged more than 300,000 volunteers who met the study inclusion criteria for COVID-19 vaccine trial consideration and helped them connect to studies close to where they live.
By engaging volunteers who match both the rigorous clinical and location requirements, we can improve access to clinical trials and participants’ ability to stay in these critical studies.
CVS Health is committed to ensuring that its research involving human subjects is conducted with integrity and free from any actual or apparent bias due to personal financial interests. As such, CVS Health has established policy requirements for disclosures of financial conflicts of interests and professional relationships in outside entities that would reasonably appear to be related to the research. Conflicts of interest in research may arise in situations where personal, financial, or other interests could affect, or appear to affect, the conduct of research activities. Having a conflict of interest does not imply improper conduct of research; rather, conflicts of interest must be identified and managed, reduced, or eliminated so that they do not threaten the integrity of scientific investigations and the public’s trust in research.